If the condition of syphilis is more serious, it may cause the patient to walk unsteadily. Syphilis is a sexually transmitted disease caused by the syphilis spirochete and is mainly transmitted through sexual contact, mother-to-child and blood. Most patients will develop sclerosing lymphadenitis, skin rashes, bone and joint lesions, eye lesions, neurological lesions, etc. As the disease worsens, patients may develop symptoms such as abnormal mental behavior, unsteady walking, hemiparesis, and limb coordination disorders. Syphilis is generally not self-healing, patients and sexual partners need to undergo rigorous examination and treatment after the disease, so that early detection and early treatment, which has a relatively large impact on the prognosis. Syphilis patients should choose regular hospitals for examination and treatment, regular follow-up visits to the hospital and standardized treatment in accordance with medical advice.