Whether lifelong medication is needed after thyroid nodule surgery should be judged according to the nature of the thyroid nodule and whether the thyroid function is normal after surgery. Usually, if the thyroid nodule is benign and the thyroid function is restored after surgery, lifelong medication is usually not required; if the thyroid nodule is malignant and hypothyroidism may occur after surgery, lifelong medication is usually required. If the thyroid nodule is found to be benign after pathological examination, it can be treated by nodule excision or localized thyroidectomy, etc. Thyroid function needs to be rechecked after the operation, and if the rechecking condition is good and no hypothyroidism occurs, lifelong medication is usually not required. If the thyroid nodule is found to be malignant after pathological examination and the diseased tissue is removed through surgery, hypothyroidism may occur, and it is usually necessary to control the condition through lifelong medication such as levothyroxine sodium under the guidance of the doctor. After surgery for thyroid nodules, thyroid function should be checked regularly. If hypothyroidism occurs, treatment should be carried out in time and the condition can be controlled by lifelong medication if necessary.