Generally speaking, tetanus desensitization injection is relatively safe. The so-called tetanus desensitization injection is a small amount of a tetanus vaccine injection in batches, in order to allow patients with positive allergy test to achieve the desensitization effect, and even if an adverse reaction occurs, the impact of the adverse reaction can be minimized to a large extent, so as to ensure the safety of the injection. Tetanus desensitization injection is to divide 1 ml of 1,500 IU units of tetanus antitoxin into four injections, the first time to take 0.1 ml of the original solution with 0.9 ml of saline injection; the second time to take 0.2 ml of the original solution with 0.8 ml of saline injection; the third time to take 0.3 ml of the original solution with 0.7 ml of saline injection; the fourth time to take 0.4 ml of the original solution with 0.6 ml of saline injection. Saline injection. Each injection should be given at an interval of 20 minutes and the patient should be noted whether there is any allergic reaction or other uncomfortable symptoms. If there is any discomfort, the injection should be stopped, and after the injection, the medical staff should observe the patient for more than 30 minutes to make sure that there is no discomfort before they can leave. It is worth noting that the common adverse reactions to tetanus antitoxin injection are anaphylaxis, urticaria, fever, lymph node swelling, severe allergy is prohibited, mild allergy can be considered as an alternative to desensitization injection. It is recommended that patients with the above conditions go to a regular hospital in a timely manner, and standardize the injection under the guidance of the doctor, so as not to delay the condition.