Newborns crying after vaccination may be caused by vaccine adverse reactions, needle stimulation of local tissues, etc., soothing the crying will stop, is a normal performance. If the newborn has an allergic reaction to the vaccine, colic, etc., causing crying and difficulty in pacifying, or accompanied by other symptoms, it is not normal. Some newborns who have been vaccinated may experience redness, swelling, heat and pain at the injection site, as well as fever, malaise and other adverse reactions, so the baby will appear to cry. In addition, to the newborn baby injection needle stimulation baby muscle tissue, will also make the local pain discomfort, this time the baby will also cry, these are normal phenomena, general parents to appease the baby after the crying situation will get better. If a newborn baby crying after vaccination is due to an allergic reaction caused by allergy to the vaccine, or after vaccination colic, etc., this situation is difficult to appease the baby crying, and more accompanied by other manifestations, such as generalized skin rashes, respiratory difficulties, more than considered not a normal phenomenon. It is recommended that newborns who cry and are difficult to appease after vaccination need to seek medical attention, and the doctor will determine whether it is normal according to the newborn’s condition.