Hepatic coma, i.e. coma caused by hepatic encephalopathy, can be relieved by removing causative factors, maintaining liver function, promoting ammonia metabolism and regulating neurotransmitters. 1. Remove triggers: actively correct electrolyte disorders such as hypokalemia, pay attention to patients’ nutritional support, and the amount of diuretics should be moderate. Use antibiotics such as levofloxacin and azithromycin to prevent and control infection. Take lactulose orally to keep the bowel clear and prevent constipation. 2. Maintain liver function: use liver-protecting drugs such as bisacodyl, glutathione and other drugs. 3. Promote ammonia metabolism: often use L-ornithine-L-aspartic acid, arginine, etc. to accelerate ammonia metabolism. 4. Regulate neurotransmitters: Flumazenil, branched-chain amino acids, etc. can be used to reduce the formation of pseudo-neurotransmitters. Patients should consult a doctor as soon as possible, and improve relevant examinations such as blood routine, liver and kidney function, etc., to assess the condition. The above mentioned drugs should be taken under the guidance of professional doctors.