The wall of sebaceous cysts is usually not intact when there is pus. Sebaceous cysts are prone to infection and suppuration under the stimulation of local extrusion and other stimuli, and may appear around the sebaceous cysts with redness, heat, pressure and pain, etc. You can use topical mupirocin ointment, ofloxacin cream and other medicines under the guidance of the doctor, if accompanied by localized redness and swelling, you can take azithromycin capsule, cephalosporin and other medicines orally under the guidance of the doctor to treat it. Sebaceous cysts with pus can also do sebaceous cysts pus drainage, drainage will immediately reduce the symptoms, may destroy the cyst wall, it is recommended to timely surgical radical excision treatment to avoid recurrence. Prohibit smoking and alcohol, avoid overwork, eat less spicy and stimulating greasy food, avoid eating seafood, need to rest, improve immunity, eat more fresh fruits and vegetables, and develop good living habits and eating habits. If you feel unwell, consult a doctor in time and take active treatment, so as not to delay your condition.