Fetal bilateral choroid plexus echogenicity is normal or not need to carry out further examination and observation to determine, fetal bilateral choroid plexus echogenicity is mostly considered to be fetal choroid plexus cysts, there are the following two specific situations. 1. Physiologic fetal choroid plexus cysts: small cysts in the choroid plexus of the lateral ventricles can be easily seen under ultrasound in the process of fetal development during the 14-24 weeks of gestation; such cysts usually disappear within 26-28 weeks of gestation, which is a physiologic situation and can be observed regularly. 2. Pathological choroid plexus cysts: if the cysts are relatively large and have existed for a long time, we should be alert to the possibility of chromosomal abnormality, and need to carry out amniocentesis or umbilical cord blood test, and if necessary, we can do fetal cranial magnetism to exclude chromosomal abnormality, such as fetal 18-trisomy, 21-trisomy and other chromosomal anomalies. It is recommended to take into account the patient’s specific family history, reproductive history, and various examinations during pregnancy, and carry out standardized and comprehensive perinatal health care under the guidance of the doctor to ensure the health of the fetus.