Smallpox vaccination is no longer available. There are no more clinical cases of smallpox, so there is no longer any need for mandatory smallpox vaccination. Smallpox vaccine is a vaccine made from cowpox virus after attenuated treatment and then produced by special techniques and technology. Its main effect is to induce the inoculated person’s body to produce specific antibodies to prevent smallpox virus infection. China began a large-scale smallpox vaccination program in 1950 to control smallpox epidemics, and the last case of smallpox in China disappeared in 1961. in May 1980, the World Health Organization declared the eradication of smallpox, and in 1981 China announced that smallpox vaccinations were to be discontinued, and the relevant smallpox vaccines had been sequestered.