Both eszopiclone and alprazolam are benzodiazepine anxiolytics, and their main effects are not very different. However, older people are more sensitive to alprazolam and need to start with a smaller dose of alprazolam. Both eszopiclone and alprazolam are relatively common medications used to treat anxiety and depression. Alprazolam is a long-acting medication that works slowly but lasts for a longer period of time. Alprazolam is a short-acting drug that lasts for a shorter period of time, but works faster and is more suitable for people with insomnia. In addition, the elderly are more sensitive to alprazolam and need to start with a small dose when using it. When taking eszopiclone and alprazolam, some adverse reactions may occur, such as weakness, drowsiness, headache, dizziness and other symptoms. It should be used with caution in patients with myasthenia gravis and severe respiratory conditions. Note that both drugs should not be used for a long period of time because of addictive properties. They should not be stopped suddenly after long-term use, but should be gradually reduced and discontinued. When taking eszopiclone or alprazolam, the elderly should be used under the guidance of a professional doctor to avoid private use of the drug, which can cause adverse reactions.