In the liver function test white globule ratio refers to the ratio of plasma albumin and globulin is low, mostly consider liver, kidney injury or autoimmune disease, etc.. 1. Liver injury: patients with liver disease often have low albumin to globulin ratio, especially for patients with severe chronic hepatitis, cirrhosis and other severe hepatitis, liver injury will reduce albumin; at the same time, the body’s immune system is activated, and globulin will increase, which will lead to low albumin to globulin ratio. 2. Kidney injury or autoimmune disease: when patients have kidney disease or autoimmune disease such as rheumatoid arthritis, systemic lupus erythematosus, dry syndrome, etc., it will also lead to low white globule ratio. The test result of low white blood cell ratio alone cannot determine the cause accurately, but also needs to be combined with the medical history, related symptoms and other test results to make accurate judgment, it is recommended to clarify the cause of the disease under the guidance of the doctor and follow the doctor’s instructions to standardize the treatment.