The treatment of exogenous hepatic encephalopathy includes treating the cause, lowering ammonia, and treating the symptoms, etc. The best treatment is to give the appropriate treatment according to the specific condition.
Exogenous hepatic encephalopathy is caused by elevated blood ammonia due to increased exogenous ammonia production, resulting in hepatic encephalopathy. Commonly, such as liver failure, intestinal flora dysbiosis, high protein diet, or gastrointestinal bleeding, causing increased intestinal ammonia production.
Treatment of the cause includes aggressive liver protection and enzyme-lowering therapy (monoammonium glycyrrhizinate, etc.) for liver failure. Dysbiosis of intestinal flora can be orally administered lactulose and norfloxacin to inhibit intestinal bacteria. Gastrointestinal bleeding requires active hemostatic treatment. Avoid high protein diet.
Ammonia-lowering treatment includes the use of lactulose or weak acid solution retention enema to remove ammonia-containing substances in the intestines, to maintain the pH in the intestines at 5~6 acidic environment, and to reduce the absorption of ammonia. Intravenous use of acetylglutamide, monosodium glutamate, arginine, etc., has a certain effect of lowering blood ammonia.
Symptomatic treatment includes the use of mannitol and furosemide in the presence of cerebral edema to reduce cerebral edema and lower intracranial pressure.
In the presence of exogenous hepatic encephalopathy, prompt medical attention is recommended, and medications need to be used under the guidance of a specialized physician.