Breast cancer PR60% is defined as 60% positive cellular staining for progesterone receptor in immunohistochemistry experiments, indicating positive and high expression of progesterone receptor. Molecular typing of breast cancer based on sex hormone receptor, human epidermal growth factor receptor, and Ki67 can provide a reference for the selection of endocrine therapy, chemotherapy, and other regimens, as well as the prognosis of the efficacy situation. Sex hormone receptors include estrogen receptor (ER) and progesterone receptor (PR). Immunohistochemical examination can detect the expression of PR, the positive rate of PR expression refers to the proportion of tumor cells with positive staining after immunohistochemical staining to the total number of cells detected, and PR60% means that 60% of the cells have positive staining. A positive staining of ≥1% after immunohistochemical staining indicates positive PR expression in breast cancer, and 20% is generally considered as the cut-off value for high or low expression in PR positive expressers. The cut-off value is also related to different pathological laboratory centers and different experimental methods, and should be judged in conjunction with the cut-off value of the local hospital. It is recommended that patients should consult with specialists and choose the appropriate treatment plan according to molecular typing and tumor stage.