High urinary creatinine needs to improve the relevant examination to clarify the cause of the disease, and treatment for the cause of the disease. If it is caused by physiological reasons, after removing the influencing factors, the urinary creatinine can be restored to normal, usually no special treatment is needed. If it is caused by pathological reasons, such as early diabetic nephropathy, acromegaly, etc., it needs to be treated with medication and surgery.
1. Physiological reasons: some patients have higher muscle content, usually eat more meat, resulting in higher blood creatinine, after metabolism of urinary creatinine also increase accordingly, or strenuous exercise leads to increased metabolism, which further causes glomerular filtration rate to increase, thus making urinary creatinine transiently increase, change lifestyle habits or rest can be improved, usually no special treatment is needed.
2. Pathological causes: such as early diabetic nephropathy, acromegaly, etc. can also lead to increased urinary creatinine. Common therapeutic drugs for diabetic nephropathy include ACEI or ARB drugs such as captopril and irbesartan to lower blood pressure and reduce proteinuria, as well as glucose-lowering drugs such as metformin, etc. Surgical resection is the first choice for the treatment of acromegaly, such as resection of pituitary adenomas by transsphenoidal surgery.
All of the above medications should be used under the guidance of a doctor, avoid self-medication. If the patient found that the urinary creatinine is elevated, it is recommended to go to the regular hospital in a timely manner, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.