Cardiac hypertrophy is a manifestation of a variety of diseases, and there is a lack of definitive preventive measures. It is recommended that residents of highland areas adjust their lifestyles and take medication when necessary, among other things, in order to help reduce the risk of plateau heart disease. Plateau heart disease refers to a type of heart disease that occurs when a person first arrives at a plateau or moves to a plateau, under the influence of low oxygen and other natural environments, which increases the resistance of the pulmonary circulation, produces pulmonary hypertension, and eventually leads to right heart hypertrophy and heart failure. Hypoxia is the causative factor of this disease, while cold, smoking, overwork, upper respiratory tract infections are the triggering factors of this disease. 1. Adjust the lifestyle: always have an oxygen cylinder, avoid strenuous exercise after entering the plateau, reduce the amount of labor as well as the intensity of labor, and gradually increase the amount of labor after adapting to it; at the same time, pay attention to preventing the cold and preventing and controlling the upper respiratory tract infections, and try to avoid smoking and alcohol. 2. Taking medication: Consider choosing a diuretic to prevent fluid retention 1~2 days before entering the plateau, please follow the doctor’s instruction. If you feel unwell in the plateau area, you should consult a doctor in time to take corresponding measures.