Difficulty in getting rid of cough may be due to the lack of treatment for the cause. Cough is commonly caused by drug factors, respiratory diseases, digestive diseases, circulatory diseases, etc., which need to be treated with general treatment, drugs or surgery. 1. For medications such as captopril and other angiotensin-converting enzyme inhibitors, angiotensin receptor antagonists such as telmisartan can be used to replace the cough as prescribed by the doctor. 2. For respiratory system diseases, such as chronic bronchitis, need to follow the doctor’s advice oral aminobromine and other expectorants, aminophylline and other antispasmodic asthma drugs, nebulized inhalation budesonide and other glucocorticoids, and so on. 3. For digestive system diseases, such as reflux esophagitis, oral domperidone and other gastric stimulants, omeprazole and other acid inhibitors as prescribed by the doctor; if drug treatment is ineffective, anti-reflux surgery can be considered. 3. For circulatory diseases, such as mitral stenosis, oral antibiotics such as benzylpenicillin and diuretics such as furosemide can be taken as prescribed by the doctor; for those who are not effective in conservative treatment, valve repair or mitral valve replacement can be considered. It is recommended that people with frequent coughing go to the hospital in a timely manner, to clarify the cause, and to standardize the treatment under the guidance of the doctor, so as not to delay the condition. The use of drugs need to follow the doctor’s advice.