The first thing you should do is to identify the cause of the ankle joint gurgling, and then proceed to physical therapy, medication, or surgery. The causes of ankle joint gurgling include physiological factors, osteoarthritis, synovitis, trauma, etc. It is recommended to identify the causes of the disease before treatment, and then carry out targeted treatment. 1. Physiological factors: the ankle joint cavity is under negative pressure, when the ankle joint is squeezed, it is easy to cause changes in the pressure in the joint cavity, causing physiological popping, usually not accompanied by other uncomfortable symptoms, without treatment. 2. Osteoarthritis: Bone cells are damaged by various factors, inducing degenerative changes in the joints and secondary osteophytes. Drugs such as aminoglycosan chondroitin can be used to slow down the degeneration of cartilage, and sodium vitrate can be injected into the joint cavity to lubricate the joints if necessary. 3. Synovitis: it is a kind of aseptic inflammation, which can cause the ankle joints to cluck and rattle, and can be relieved by red light therapy, localized hot compresses to alleviate the uncomfortable symptoms, but also can take non-steroidal anti-inflammatory drugs ibuprofen to ease the pain. 4. Trauma: If there is a break in the skin, it is necessary to clear the wound in time, and if there is a fracture, it is necessary to reset, immobilize and rehabilitate in time. The cause of ankle joint gurgling more causes, but also may be related to bursitis, osteophytes and other factors, if the symptoms continue to have no relief, it is recommended to go to the hospital in a timely manner to find out the cause of the disease, by the doctor targeted treatment, the use of medication, please follow the doctor’s instructions.