Hepatic coma, i.e. hepatic encephalopathy, is one of the main causes of death in patients with liver disease, and requires general treatment, drug treatment, and surgical treatment to improve the prognosis.
1. General treatment: in acute stage, it is necessary to prohibit or limit the intake of protein food, deamination, acidification of intestines, lactulose enema, etc. to reduce the absorption of ammonia, and remove toxins in intestines; at the same time, it is necessary to pay attention to rest, avoiding strenuous activities and exertion; timely search for triggering factors, and remove them in time.
2. Medication: Under doctor’s guidance, antibiotics such as rifaximin should be applied to inhibit the reproduction of intestinal flora and reduce the number of ammonia-producing bacteria; L-Ornithine and L-Menthionine should be applied to reduce the ammonia in the blood circulation; at the same time, probiotics and other micro-ecological agents should be applied to promote the growth of intestinal beneficial flora and alleviate the symptoms.
3. Surgical treatment: Liver transplantation and artificial liver treatment can be considered for patients who have poor effect of internal medicine treatment and recurrent episodes.
It is recommended that patients with hepatic coma should consult the doctor in time to find out the cause and get early treatment under the doctor’s guidance to improve the prognosis.