Black spots on the glans with no pain or itching may be caused by nevus melanosus, or may be caused by melanoma, or may be caused by the use of hormonal drugs that produce hyperpigmentation, the causes are different, the treatment methods are different. 1. Melanotic nevus: Melanotic nevus is a kind of benign proliferative disease of melanocytes, which can cause patients to have black spots on the glans, painless and itchy symptoms, and the treatment can be carried out through surgery, laser and other methods. 2. Melanoma: Melanoma is a kind of tumor caused by malignant proliferation of melanocytes, which can also lead to black spots on the glans, painless and itchy symptoms, and can be treated by surgery, chemotherapy, molecular targeting therapy and other methods. 3. Drug-induced: after using glucocorticoid ointment such as budesonide ointment and hydrocortisone ointment, hyperpigmentation can occur at the site of use, therefore, it can also lead to symptoms of black spots on the glans without pain or itching, which can be relieved by stopping the use of glucocorticoid ointment. In addition to the above factors, other reasons can also lead to the symptoms of black spots on the glans, painless and itchy, if the symptoms continue to be unrelieved or accompanied by other discomforts, it is recommended to consult a doctor in a timely manner to find out the cause of the problem, and under the guidance of the doctor treatment.