A small hole in the drain wound that has not healed is considered to be poor wound healing caused by infection, and medication can be taken to promote healing. Drainage tubes are generally used to expel pus, blood and other fluids from the patient’s body after surgery, and after removing the drain, a local wound will appear, which, if not taken care of, may lead to bacterial invasion of the wound, thus causing a local infection. Due to the presence of inflammation, the wound may not be able to heal for a long time, thus causing a small hole in the drain wound that never heals. Patients go to the hospital in time to improve the relevant examination, clear for infection, under the guidance of the doctor can be regularly rinsed and disinfected, placed in iodine oil gauze drainage pus, and take amoxicillin, cefaclor and other antibiotics for treatment. At the same time, we should pay attention to keep the wound clean and dry, avoid strenuous exercise, and change the medicine regularly, which is conducive to promoting wound healing. If there is a situation that the drain wound has not healed, it is necessary to consult a doctor for diagnosis in time to avoid aggravation of the wound.