Itchy skin on both sides of the vulvar lips of a woman may be caused by vulvar eczema, pruritus, and other diseases, the treatment includes general treatment, medication and so on. 1. Vulvar eczema: vulvar eczema may cause itching on both sides of the lips of the vulva, the patient must not scratch the lesions to avoid breakage and infection. You can follow the doctor’s instructions to use topical tretinoin, mometasone furoate and other glucocorticoid ointment, with anti-inflammatory and anti-itching effect. Or tacrolimus and other calcium-modulated phosphatase inhibitors. If the itching is severe, oral antihistamines such as loratadine are needed. 2. Pruritus: Pruritus of vulvar skin is mostly related to vaginal trichomoniasis, gonorrhea, diabetes mellitus and cervical cancer, and may also be related to endocrine disorders. If it is caused by trichomonas infection, it can be treated with metronidazole suppository, tinidazole suppository and other drugs. Itching caused by other diseases should be treated according to the cause. It is recommended that patients go to the hospital for relevant examinations, clear diagnosis, choose the appropriate way to deal with, the specific use of drugs need to follow the doctor’s instructions.