Pain in the middle of chest after meal may be esophageal cancer, reflux esophagitis, gastritis, coronary heart disease, etc., and one should consult doctor in time to find out the cause. 1. Esophageal cancer: malignant tumor of esophagus blocks the lumen of esophagus, causing narrowing of the lumen and repeated stimulation of the tumor after eating, which may cause choking sensation and pain and discomfort after meals. 2. Reflux esophagitis: Reflux esophagitis is an inflammatory disease of the esophagus caused by the reflux of gastric and duodenal contents into the esophagus. Excessive secretion of gastric acid usually burns the esophageal mucosa. When the esophageal mucosa is damaged, it will lead to reflex chest pain and pain in the middle of the chest after eating. 3. Gastritis: Gastritis is an acute and chronic inflammatory disease of the gastric mucosa caused by a variety of causes. If patients with gastritis eat cold, spicy and irritating food, it will usually cause irritation to the mucous membrane of the esophagus and cause pain in the middle of the chest after eating. 4. Coronary heart disease: coronary heart disease refers to coronary artery atherosclerotic heart disease, coronary heart disease patients after eating, the whole body blood flow to the gastrointestinal tract, due to the narrowing of the coronary artery lumen, the heart is more susceptible to ischemia, easy to make the patient appear to appear in the middle of the chest pain, chest tightness and other symptoms. Chest pain right in the middle of the chest after a meal may also be caused by other factors, it is recommended that the patient consult a doctor in a timely manner, by the doctor to clarify the cause of the disease, to give targeted treatment.