Leukemia m4 has a cure. Leukemia m4 type, also known as acute granulocyte-monocyte leukemia, through standardized treatment, some patients can achieve clinical cure. Leukemia m4 is a malignant clonal proliferation of granulocytes and monocytes at the same time, leading to abnormal hematopoietic function, resulting in fever, hemorrhage, anemia, organ damage and other clinical symptoms, the prognosis is poor. Clinically, m4 leukemia can be cured by induction chemotherapy and then hematopoietic stem cell transplantation. Hematopoietic stem cell transplantation is to input hematopoietic stem cells from allogeneic bone marrow into the patient’s body to rebuild the hematopoietic function and immune function of the patient’s bone marrow, so as to cure m4 leukemia at the stem cell level. Specific drugs include cytarabine, flexerodine, fludarabine, leucovorin, and so on. Therefore, once diagnosed, patients with m4 leukemia should actively cooperate with clinical treatment, reduce the number and proportion of leukemia cells through chemotherapy, and strive to achieve disease remission, and patients in the high-risk group can do hematopoietic stem cell transplantation as early as possible to prolong the survival period. Specific diagnosis and treatment should be carried out under the guidance of physicians.