Eczema on hands and feet may be caused by external and internal factors, and need to go to the hospital in time for treatment. 1. External factors: (1) food allergy: eczema on hands and feet may be caused by food allergy, due to excessive intake of food containing protein, such as fish, shrimp, beef and mutton, causing abnormalities in the body’s immune system, food allergy will appear after the itching of the skin, eczema, erythema and other symptoms. (2) Environmental factors: eczema on hands and feet may be caused by environmental factors, such as pollen, air, dust, hot and humid living environment, etc., may lead to eczema. (3) Chemical substances: Eczema on the hands and feet may be caused by chemical substances, which may arise from contact with cosmetics, synthetic fibers, and soaps. 2. Internal factors: Eczema on hands and feet may be triggered by chronic infections, endocrine and metabolic changes, and blood circulation disorders. It should be noted that eczema on the hands and feet should follow the doctor’s instructions to standardize the treatment, do not blindly use medication, so as not to delay the condition or adverse reactions, and at the same time to stay away from allergens, away from chemical substances.