Vitiligo does not have the latest treatment, generally need to be relieved through drug treatment, surgical treatment and physical therapy to improve. 1. medication: patients can use tacrolimus ointment, pimecrolimus cream and other calcium-modulated phosphatase inhibitors or mometasone furoate, hydrocortisone butyrate cream and other glucocorticoid creams under the guidance of the doctor. When the disease is in the progressive stage, you can take oral hormone drugs such as prednisone, dexamethasone and so on, or combined with immunosuppressants such as cyclosporine. 2. Surgery: If the patient’s vitiligo symptoms are relatively stable, other methods of treatment is not effective, but also through their own body surface epidermal transplantation, tiny pieces of skin transplantation or single hair follicle transplantation and other surgical treatment. 3. physical therapy: such as phototherapy NB-UVB and 308nm excimer laser/light is suitable for all types (except mucous membrane type), all stages of vitiligo treatment. Large area irradiation need to pay attention to the eyes, face and external genitalia protection. Vitiligo patients in the process of treatment, should pay attention to self-regulation, follow the doctor’s prescription medication, and regular review, do a good job of monitoring the condition, when the body appeared to be unsuitable for timely access to medical treatment, to take targeted therapeutic measures, to avoid misunderstanding the condition of the adverse effects.