The penis is swollen into a gummy swelling, there is itching for syphilis stage III. Generally untreated or inadequately treated for early syphilis formation, usually need to inject penicillin treatment. Syphilis is a chronic disease formed by the syphilis spirochete. It is mainly transmitted through sexual contact, mother-to-child transmission, and blood transmission. Generally, the third stage of syphilis is formed by inadequate treatment of early syphilis, and it is advanced syphilis. The course of the disease is generally > 2 years. Stage III syphilis is marked by syphilitic dendritic swelling, also known as syphiloma, which is the most destructive type. It is usually treated with benzylpenicillin, given intramuscularly in both buttocks, or procaine penicillin intramuscularly. Penicillin can be taken orally with doxycycline if you are allergic. If a penile dendritic swelling occurs, do not self-medicate, you need to see a doctor as soon as possible, follow the doctor’s instructions for medication to avoid complications.