Choledocholithiasis is usually asymptomatic or has only epigastric discomfort. When the stone causes obstruction of the bile duct, abdominal pain or jaundice may occur, and if secondary to inflammation of the bile duct, there may be three more typical symptoms (medically referred to as Charcot’s triad): abdominal pain, chills and high fever, and jaundice in the manifestation of jaundice. Generally, patients with choledocholithiasis have no obvious symptoms, or only epigastric discomfort. If the stone causes obstruction of the bile duct and inflammation of the bile duct, the patient will have obvious symptoms. Abdominal pain: most suggest that the stone has caused bile duct obstruction, the smooth muscle of the common bile duct or sphincter of Oddi spasm. The pain is usually confined to the lower part of the sternum and the right upper abdomen, and is persistent and severe. The pain may affect the back of the right shoulder, and the patient may also feel pain in the back of the right shoulder, accompanied by nausea and vomiting. Chills and high fever: seen in gallstones obstructing the bile duct combined with infection, usually manifested as flaccid fever, body temperature is often above 39 ℃, the lowest body temperature is still higher than the normal body temperature. Jaundice: mostly suggests that the stones have caused bile duct obstruction, but also seen in patients with secondary bile duct inflammation. The first manifestation is obvious yellow urine, followed by sclera (i.e. “white of the eye”) yellow, yellow skin, yellow skin can be accompanied by itching. In some patients, the symptoms of stone ingrowth are not serious, and the jaundice can be relieved on its own. If the above symptoms occur, patients should consult the doctor in time, complete the relevant examinations, make a clear diagnosis, and then take the appropriate treatment plan.