Pregnant women who are positive for group B streptococci should be targeted with antibiotics such as penicillin and cefazolin when premature rupture of membranes occurs or when they enter labor. A pregnant woman who is positive for group B streptococcus is one who has a positive culture for group B streptococcus from a sample taken during pregnancy from the vagina, rectum, or perianal area, which may lead to neonatal infections, sepsis, and central nervous system infections if not intervened. Generally all pregnant women between 35 and 37 weeks of gestation are screened for group B streptococcus. Pregnant women who are screened at 35 to 37 weeks of gestation and found to be positive for group B streptococcus should be given antibiotics prophylactically in the event of premature rupture of membranes or upon entering labor. Penicillin can be given intravenously; if penicillin is allergic or the skin test is positive, antibacterial drugs such as cefazolin and clindamycin can be used. All of the above drugs should be used according to the doctor’s prescription, do not use the drugs at your own discretion, in order to avoid the occurrence of adverse events.