General anesthesia to extract four wisdom teeth at a time is more risky, but the overall risk can be controlled. 1. The extraction itself is a surgery, the more teeth extracted, the greater the risk. If the patient’s health is better, there is no systemic disease, the risk of extraction will be appropriately reduced; the patient’s health is poorer and combined with some systemic diseases, such as hypertension, heart disease, high blood sugar, etc., if the extraction of four teeth at a time may be cardio-cerebral and cerebral vascular accidents or extraction wounds do not heal. 2. If the four teeth extracted are teeth other than wisdom teeth, the risk will be smaller. If the four teeth extracted are wisdom teeth, the mandibular wisdom teeth may damage the inferior alveolar nerve and cause numbness, etc., and the maxillary wisdom teeth may form a maxillary sinus fistula. If you want to extract four teeth at a time, it is best to visit a specialized hospital to assess the patient’s condition and the teeth before determining the best extraction plan, which can mitigate the risk of tooth extraction.