Swollen and itchy mosquito bites can be treated by applying ointments such as calcium-modulated phosphatase inhibitors like tacrolimus ointment, glucocorticoid ointments like tretinoin cream, antibiotics such as mupirocin ointment and antipruritic agents like glycerine lotion. When the patient is bitten locally by mosquitoes and accompanied by swelling and itching symptoms, it can be improved first by washing with running water or soapy water and applying ice locally. If the above measures can not be improved, the application of glycerine lotion and other antipruritic agents, tacrolimus ointment and other calcium-modulated phosphatase inhibitors to achieve astringency, swelling and itching purposes as prescribed by the doctor. For some of the redness, swelling, itching symptoms are serious, if necessary, the application of tretinoin cream, hydrocortisone butyrate cream and other glucocorticoid cream treatment. If accompanied by the phenomenon of bacterial infection, can also be combined with the application of erythromycin ointment, mupirocin ointment and other antibiotic treatment. It is recommended that patients apply the ointment under the guidance of a physician, and should not use the medication on their own. When the skin is itchy, patients should not scratch with their hands, so as not to aggravate the condition by breaking the skin.