Rashes on both sides of the thighs are mostly caused by eczema, ringworm, urticaria, etc. They can be treated with topical anti-swelling and anti-itching drugs, anti-fungal ointment, and oral anti-allergy drugs. 1. Eczema: a chronic inflammatory skin disease, early manifestations of erythema, pimples, etc., can be applied locally glycerine lotion, zinc oxide cream, hydrocortisone butyrate cream, etc., with the role of itching and swelling, and if necessary, oral antihistamine drugs, such as chlortetracycline, etc. treatment. 2. ringworm: mostly caused by fungal infection, mostly manifested as ring-shaped erythema, erythema covered with scales, can be applied locally antifungal drugs, such as miconazole nitrate ointment, fluconazole cream, etc., and oral itraconazole and other medications when necessary. 3. Urticaria: generally due to genetic, allergy and other factors, manifested as wind, erythema, pay attention to avoid their own allergic factors, you can take anti-allergic drugs, commonly used drugs such as loratadine, cetirizine. Rash on both sides of the thighs is recommended to consult a doctor in a timely manner, and follow the doctor’s instructions to deal with. The above drugs need to be used under the guidance of a doctor.