Adrenocortical hyperplasia in newborns generally refers to newborns with congenital adrenocortical hyperplasia, and the treatment methods include medication and surgery. 1. Drug treatment: children with salt loss need intravenous saline supplementation; children with metabolic acidosis need to be treated with sodium bicarbonate and 0.45% sodium chloride; children with severe salt loss can be treated with hydrocortisone; long-term use of hydrocortisone and other saline corticosteroid as well as glucocorticosteroid such as hydrocortisone is also needed to carry out synergistic treatment. 2. Surgery: For children with female hermaphroditism, partial clitoridectomy or orthopedic surgery is recommended between the ages of 6 months and 1 year. Children diagnosed with congenital adrenocortical hyperplasia are recommended to receive standardized treatment under the guidance of a doctor.