Gray nail clinic is generally not recommended to use only topical drugs for treatment, need to be combined with the application of oral drugs for treatment. Gray nail is caused by fungal infection, mainly manifested in the nail plate appears cloudy, thickening, atrophy, warping, shedding and other symptoms. Gray nail patients who do not take medication, only the use of topical drugs applied to the nail, easy to lead to poor efficacy, which is due to the external drugs can not be very good penetration to the whole nail, the clinical general recommendation of oral medication and topical drugs used in conjunction, can significantly improve the cure rate, reduce the risk of adverse reactions. Gray nails are stubborn, difficult to treat and prone to recurrence, once diagnosed, it is recommended to go to the hospital in time for treatment.