MMR and HFMD vaccines are not recommended to be given at the same time. It is recommended to leave more than two weeks between the two vaccines. Both MMR and HFMD vaccines are effective in preventing viral infections by injecting attenuated or inactivated pathogens directly into the body, thereby effectively stimulating the immune system to produce appropriate antibodies. Any vaccination may result in adverse reactions such as allergy, localized redness and swelling, subcutaneous nodules or itching at the site of vaccination. Since all vaccines have a certain chance of having adverse reactions to the vaccination after vaccination. Therefore, if two vaccinations are administered at the same time, the adverse reactions may be aggravated or more serious vaccine toxicity may occur. Therefore, it is not recommended to administer the MMR and HFMD vaccines at the same time without the need for simultaneous vaccination, which can be done more than two weeks apart. Medical advice should be sought when administering the MMR, HFMD or other vaccinations.