Nitroglycerin and aspirin can be used together, but are taken differently. The main role of nitroglycerin is to dilate the coronary arteries, the main use is sublingual, mainly used for angina pectoris emergency treatment. Aspirin is a drug that inhibits platelet aggregation, which is the basic drug for coronary heart disease, and can prevent angina and myocardial infarction attacks, mainly taken orally. There are no contraindications to combining nitroglycerin and aspirin at the same time, and they can be taken at the same time. The adverse reactions of nitroglycerin are headache, dizziness, palpitations, blood pressure drop, etc. It is forbidden for patients who are allergic to the drug components, hypotension, elevated intracranial pressure, glaucoma, etc. Adverse reactions of aspirin include stomach pain, gastric bleeding, bleeding from skin mucous membranes, cerebral hemorrhage, bleeding from the urinary tract, etc. It is contraindicated in patients with allergy to the drug components, aspirin-related asthma, active bleeding, active ulcers and so on. When combining nitroglycerin and aspirin, the drug should be used under the guidance of a physician to choose the appropriate dosage and usage.