Causes of enlarged lymph nodes include inflammation, tuberculosis, lymphoma and tumor metastasis. When anti-inflammatory drugs are ineffective, it is recommended to receive further examination to clarify the cause of the disease and then treat the cause. 1. Inflammation: Lymph node enlargement caused by inflammation can be controlled by antibiotics such as penicillin, doxycycline, levofloxacin and other drugs to improve the symptoms. Conventional anti-inflammatory drugs are effective for lymph node enlargement caused by bacterial infections, while those caused by viruses have no obvious effect, and need to take antiviral drugs such as ribavirin to improve the symptoms. 2. Tuberculosis: Lymph node enlargement caused by tuberculosis requires standardized treatment with anti-tuberculosis drugs such as isoniazid, rifampicin and ethambutol. 3. Lymphoma: lymph node enlargement caused by lymphoma can be treated with chemotherapy drugs such as cyclophosphamide, fluorouracil, cytarabine and so on. 4. Tumor metastasis: Lymph node enlargement caused by metastasis of malignant tumors is recommended to be treated with radiotherapy, chemotherapy and targeted therapy to improve the prognosis of the disease. Due to the individual differences and the diversity of causes, anti-inflammatory drugs are ineffective in the case of identifying the cause of the cause of the disease can be actively on the cause of accepting standardized treatment, the drug is recommended to be used in strict compliance with the doctor’s instructions, the emergence of adverse reactions recommended to consult the doctor, drug allergy is prohibited.