Determining whether a spider bite is toxic or not depends on the specific reaction at the site of the bite and the specific species of spider, and a doctor should be consulted and medical attention sought. After being bitten by a spider, if the spider itself carries animal toxins, the bite site will usually show more obvious redness, swelling and pain, and subcutaneous elevation. In severe cases, there may be pus or localized infection at the bite site, which may cause nerve damage. Generally, when there is more severe pain or tissue damage and ulceration at the bite site, it is necessary to suspect that there is a toxic reaction at the bite site. Spider bites also require prompt medical attention and consultation with a physician to find out if the specific spider species itself carries any biological toxins. If the spider species carries a biological toxin and the bite site is in obvious discomfort, detoxification should be carried out in a timely manner, which can be quickly eradicated by local injection of an antidote serum. After being bitten by a spider or other animal, medical attention should be sought and the wound should be cleaned promptly.