Vaccination site redness, swelling and itching usually belongs to the normal post-vaccination adverse reactions, should pay attention to not scratching, avoiding water, towel localized hot compresses can promote swelling, apply iodine povidone and so on to stop itching. After vaccination, the most likely post vaccination adverse reactions are redness, swelling, itching and pain at the site of vaccination. These symptoms are normal post vaccination adverse reactions, generally within 3 days after vaccination can be relieved or subside. The redness, swelling and itching at the vaccination site after vaccination should not be scratched, as the fingernails may contain many kinds of bacteria, and scratching may cause bacterial infection at the vaccination site. Be careful not to get wet, water will not only aggravate the redness and swelling, but also may cause infection. If the redness, swelling and itchiness are more obvious, hot towels can be used to apply localized hot compresses, which is conducive to the promotion of blood circulation here, and is conducive to the subsiding of redness, swelling and itchiness. In addition, the application of iodine povidone or glycerine lotion is conducive to the relief of itching symptoms. The medication should be applied reasonably according to the doctor’s prescription.