Infants always twisting and turning in their sleep may be caused by certain physiological factors, or pathological factors, such as vitamin deficiencies, intestinal spasms and so on. 1. Physiological factors: Because the development of the infant’s nervous system is not yet perfect, it is easy to be stimulated by sound, touch and other stimuli, and appear to sleep twisting around. In addition, if the baby is in a hungry state, or the indoor temperature is too high, too tight clothes, etc., so that the baby feels uncomfortable, can also appear to sleep always twisting around. 2. Pathologic factors: (1) Vitamin D deficiency: under the induction of insufficient intake of vitamin D, insufficient sunlight exposure and malabsorption, it is easy to cause vitamin D deficiency in infants. Affected children may have symptoms such as sleep disturbance, night terrors, irritability, and so on, thus appearing to sleep all the time twisting and turning, and may also lead to occipital baldness due to shaking the head and rubbing the pillow, and then have skeletal changes and delayed motor development. (2) intestinal spasm: intestinal spasm is the most common disease in pediatric acute abdominal pain, with sudden onset of abdominal pain as the main manifestation of the child may appear in severe cases of crying, rolling, accompanied by pallor, or vomiting and other symptoms. Babies always twist around in their sleep, there may be other reasons, it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.