Left adrenal gland thickening is harmful to the body if it is seen in pathological factors such as pheochromocytoma, primary aldosteronism, cortisolism, etc. Blood hypertension, heart failure, diabetes mellitus, etc. may occur. In addition, certain adrenal gland enlargement can be manifested as non-functional, generally does not cause harm to the body, regular review can be. 1. Pheochromocytoma: a large amount of catecholamines will cause paroxysmal blood pressure significantly increased, accompanied by severe headache, profuse sweating, tachycardia and epigastric pressure, which will cause shock in severe cases, causing serious damage to the cardiovascular and cerebral vessels. 2. Primary aldosteronism: increased secretion of aldosterone will also lead to increased blood pressure, which is gradually increased, in addition to the lowering of blood potassium will feel muscle weakness, cyclic paralysis, and in severe cases, it will cause respiratory distress and dysphagia. If left untreated, it will lead to cardiac hypertrophy, heart failure, impaired renal function and so on. 3. Cortisolism: adrenocortical hyperplasia will lead to excessive glucocorticoids, resulting in full moon face, buffalo back, purple lines on the abdomen or inner and outer thighs, and abnormal glucose metabolism will lead to steroidal diabetes mellitus, damaging the cardiovascular and cerebral vascular, metabolic system, bones, and so on. In addition, certain adrenal gland thickening can be manifested as non-functional, usually does not cause damage to the body, regular review can be. Left adrenal gland thickening should be timely regular hospital consultation, communicate with the doctor, do further examination, combined with the clinical symptoms of comprehensive diagnosis, early treatment, to avoid causing adverse consequences.