The use of clotrimazole preparations flow out especially itchy may be due to the primary disease of fungal vaginitis, but also may be due to the adverse reaction of the drug, and may be due to the patient’s allergy to clotrimazole. 1. Fungal vaginitis: fungal vaginitis this disease itself can lead to patients with symptoms of vulvar itching, so in the condition has not yet been relieved, the patient can appear after the use of clotrimazole preparation flow out of the special itchy symptoms. 2. Adverse drug reactions: if the use of clotrimazole preparations, the symptoms of itching worsened after the drug flow out, may be due to adverse drug reactions, this adverse reaction is usually a transient irritation, can be relieved on their own. 3. drug allergy: allergy to clotrimazole preparations may also lead to the use of clotrimazole preparations flow out of the special itchy symptoms, in addition to patients can also appear local burning, redness and swelling of the symptoms, this situation should be timely to stop the use of drugs, and will be cleaned up the local drug, under the guidance of the physician to replace other drugs. In addition to the above factors, other reasons can also lead to the use of clotrimazole preparations flow out of the special itchy symptoms, it is recommended to consult a doctor in a timely manner to identify the causes, please doctor to deal with.