There are no contraindications between Liu Wei Di Huang Wan and Zhi Bai Di Huang Wan and they can be used at the same time, but due to the similarity in efficacy, patients are advised to choose one or the other to use. Both drugs are recommended to be taken by a professional physician. Six-flavored Dihuang Pill is composed of Radix Rehmanniae Praeparata, Rhizoma Dioscoreae, Cornu Cervi Pantotrichum, Zedoariae and other medicines, with the effect of nourishing yin and tonifying the kidneys (nourishing the yin fluid and tonifying the kidneys), it can be used to treat soreness of the waist and knees caused by kidney yin deficiency, tidal fever (a burst of heat, feeling that the heat is penetrating from the inside of the bone to the outside), night sweating (sweating abnormally after going to sleep, and stopping after waking up), and seminal emission and other diseases. Zhi Bai Di Huang Wan is composed of Zhi Mu, Huang Bai, Mudan Pi, Shan Yao and other medicines, with the effect of nourishing yin and lowering fire (nourishing yin essence and lowering fire), it can be used for treating hot flashes (a burst of heat), night sweating (abnormal sweating after going to sleep and stopping after waking up), short and red urination (small amount of urination, dark yellow in color), and dry mouth and tinnitus, which are caused by yin deficiency and fire (deficiency of yin essence and over-exuberance of deficiency and fire in the body). Between the above two drugs, there is no contraindication of efficacy and action, so they can be used together. However, there is a certain degree of similarity in their efficacy, so it is recommended to choose one of them for use under the guidance of a doctor in order to avoid excessive efficacy.