Patients with advanced liver cancer who develop cough usually have a shorter survival time. This is because tumor cells in advanced stage of liver cancer will enter the lungs and digestive system through blood circulation, which will cause continuous coughing and vomiting. Due to the damage of tumor cells to bronchial mucosa and mucosal blood vessels, the ventilation ability of patients will be seriously affected, resulting in frequent hemoptysis, which will increase the physical exertion of patients, and at the same time, the reduction of intake will shorten the life span of patients. There is a possibility of ascites, jaundice, infection, hemorrhage, hepatic encephalopathy and so on. In addition, if patients with advanced stage of liver cancer, analgesic treatment should be carried out in time. If patients have serious pain symptoms, they can improve the quality of their survival with appropriate analgesic drugs. It should be noted that patients with advanced liver cancer can reduce the adverse effects of the disease through “early detection, early diagnosis and early treatment”, and many of them may prolong their lives, so it is recommended that patients establish confidence in treatment.