Glans sensitivity is the main cause of premature ejaculation, and its treatment includes general application of medication, psychological-behavioral therapy and other methods. 1. Pharmacological treatment mainly adopts 5-HT reuptake inhibitors, lidocaine aerosol and so on. (1) 5-HT reuptake inhibitors such as Dapoxetine. These drugs prolong the ejaculation time in men. Contraindications include recent strokes and heart attacks, low blood pressure, and combining them with nitrates is prohibited. (2) Surface anesthetics: Lidocaine aerosol is generally applied to the surface of the glans, which anesthetizes the nerves and thus prolongs the latency to ejaculation. Contraindications include those who are allergic to the product are prohibited. 2. Psychological-behavioral therapy is mainly aimed at enhancing the patient’s sexual self-confidence, reducing his anxiety, and alleviating his inner lack of self-confidence. The general use of sexy concentration training method, and his wife closely cooperate, so as to restore the patient’s sexual self-confidence. In summary, the specific delay method, but also need to go to the hospital to consult the doctor, follow the doctor’s instructions to use drugs, do not blind treatment.