Gallbladder wall polyp 4cm is very serious. For 4cm gallbladder polyps, the possibility of cancer is relatively high, in addition, 4cm gallbladder polyps will also lead to a series of clinical symptoms. 1. High possibility of cancer: gallbladder polyps with a diameter greater than 1cm already belong to the category of polyps with malignant factors. 4cm gallbladder polyps have the possibility of malignant transformation. Clinically, for 4cm gallbladder polyps, patients are usually advised to undergo cholecystectomy. 2. cause clinical symptoms: 4cm of gallbladder polyp volume is already very large, will lead to the patient to appear right upper abdomen discomfort, hidden pain; also can have the right shoulder radiating pain, back radiating pain; also can appear nausea, vomiting and other performance. Clinically, for symptomatic gallbladder polyps, cholecystectomy will also be recommended. For patients who have been diagnosed with gallbladder wall polyps, they should go to the relevant departments of regular hospitals as soon as possible, and under the guidance of specialized physicians, in order to avoid delays in the condition that may lead to adverse results.