The causes of high human epididymal protein may include inflammatory reactions, endocrine diseases and tumors. 1. Inflammation: the presence of inflammation in the patient’s body will easily lead to high epididymal protein, and it is necessary to go to the hospital for a detailed examination to determine the site of inflammation, and then use anti-inflammatory drugs for treatment. 2. Endocrine diseases: endocrine diseases may lead to hormonal abnormalities, and may also lead to physiological disorders, and even glandular tumors. 3. Tumor: human epithelial protein is a kind of tumor marker, which is mainly combined with CA125 and has certain significance in the diagnosis of female ovarian epithelial cancer. Human epididymis protein also has certain sensitivity to the diagnosis of endometrial cancer. If human epididymis protein is high, you need to consult a doctor in time to find the cause of the disease, and according to the different causes of the disease under the guidance of the doctor, to avoid delaying the disease.