CK8/18(+) generally suggests that the tumor is malignant. 1. CK8/18(+) is the result of pathological immunohistochemical typing examination, positive often suggests that the tumor cells are malignant, and this result is commonly found in the typing of hepatocellular carcinoma and gastric cancer. 2. CK, cytokeratin, is an intermediate fiber. Up to now, a total of 20 types (CK1~CK20) have been found, and the expression of each type is related to the differentiation of the tissues and organs in which it is located, so immunohistochemistry of CK is often used as an important pathological diagnosis method. 3. Since tumor cells are highly invasive and infiltrative, treatment should be taken as early as possible under the guidance of professional doctors to control the further spread of tumor cells and prevent the condition from aggravating. Treatment can generally be surgery, intervention, radiotherapy, chemotherapy and so on.