Back coldness, vomiting, weakness, and black stools consider upper GI bleeding, which can be treated with oral proton pump inhibitors and hemostatic medications. Upper gastrointestinal bleeding refers to bleeding from the esophagus to the duodenum. Clinical manifestations are vomiting blood, black stools, and in severe cases, anemia and decreased blood volume, or even shock. Symptoms of decreased blood volume include dizziness, fatigue, cold sensation in the limbs, and panic. Drug treatment includes: proton pump inhibitors, such as omeprazole, pantoprazole and so on to inhibit the secretion of gastric acid, increase the PH value in the stomach can achieve the purpose of hemostasis. Hemostatic drugs, such as growth inhibitors or octreotide. Actively replenish blood volume, and those who are not effective in the treatment of the above symptoms should be hemostatic under endoscopy or vascular intervention. Those who have symptoms of gastrointestinal bleeding should go to regular hospitals as soon as possible, and use medicines under the guidance of doctors, do not blindly use medicines on their own.