Liver fibrosis is a reversible pathophysiologic phenomenon that generally has a good prognosis and does not affect the patient’s life expectancy time. However, if the disease continues to develop, the patient’s condition progresses to cirrhosis, which can threaten the patient’s life. The treatment of liver fibrosis is mainly for the cause of the disease. For example, if liver fibrosis is caused by viral hepatitis, it is necessary to remove and inhibit viral replication; if liver fibrosis is caused by parasites, it is necessary to eradicate schistosomiasis infection with medication; and if it is caused by year-round drinking, it is necessary to quit drinking immediately. Combined with hepatoprotective therapy to suppress liver inflammation, liver fibrosis is theoretically reversible and therefore does not affect the patient’s life expectancy. Patients with liver fibrosis need to establish reasonable living habits, such as controlling body weight, avoiding smoking and drinking alcohol, paying attention to hygiene, and not consuming expired and moldy food, etc., while following the doctor’s instructions.