Itchy skin whitening with itching around the anus, if it is perianal eczema, you can use dexamethasone ointment, tretinoin cream and other glucocorticoid drugs to treat; if it is vitiligo, you can use dexamethasone ointment, tacrolimus ointment, carbotenoids ointment and other improvements. 1. perianal eczema: is inside and outside a variety of factors stimulation caused by perianal skin inflammatory reaction, may cause itching around the anus, skin whitening, you can use dexamethasone ointment, tretinoin cream and other medications, itching serious can take loratadine, cetirizine and other antihistamines. 2. Vitiligo: it is a common acquired pigment loss skin and mucous membrane disease, may cause itching around the anus, white skin, can be used externally dexamethasone ointment, hydrocortisone ointment and other glucocorticosteroid medications; as well as calcium-modulated phosphatase inhibitors such as tacrolimus ointment, pimecrolimus ointment, etc.; Vitamin D3 derivative such as carbotenoids ointment, tacrolimus ointment and so on. White and itchy skin around the anus may have other causes, need to go to the hospital for examination, clear cause of the disease and follow the doctor’s prescription medication.