The treatment of pityriasis rosea sometimes dark and sometimes light in color includes systemic medication, topical medication, physical therapy and so on. 1. Systemic drug treatment: patients with obvious itching can use antihistamine drugs (such as loratadine). For patients with serious condition or long duration of disease, short-term oral glucocorticosteroid treatment can be taken in small doses. 2. Topical medication: Glycolite lotion or glucocorticoids such as hydrocortisone cream can be used locally. 3. Physiotherapy: Narrow-spectrum medium-wave ultraviolet irradiation may be effective for the progressive stage, which can shorten the course of the disease and promote the receding of skin lesions. Patients with pityriasis rosea should not use medication on their own, but should go to the hospital in time and receive standardized treatment under the guidance of the doctor.